2,3-Dichlorobenzene-1-sulfonyl chloride → HCID 10195093, compound

HRID 1444029Notes

Reaction equation

HRID 1444029 reaction equation
[CH3:1][O:2][C:3]1[C:4]([NH2:11])=[N:5][C:6]([Cl:10])=[C:7]([Br:9])[N:8]=1.[Cl:12][C:13]1[C:18]([Cl:19])=[CH:17][CH:16]=[CH:15][C:14]=1[S:20](Cl)(=[O:22])=[O:21]>>[Br:9][C:7]1[N:8]=[C:3]([O:2][CH3:1])[C:4]([NH:11][S:20]([C:14]2[CH:15]=[CH:16][CH:17]=[C:18]([Cl:19])[C:13]=2[Cl:12])(=[O:22])=[O:21])=[N:5][C:6]=1[Cl:10]

Participants

3

Reactant 2

HCID 27342222,3-Dichlorobenzene-1-sulfonyl chlorideHCID 59168121HCID 59168121, compound

Product 1

HCID 10195093HCID 10195093, compound

Procedure

Procedure as for Example 1 (reaction performed at room temperature) using 3-methoxy-5-bromo-6-chloro-2-pyrazinamine (Example 125a) (0.5 g) and 2,3-dichlorobenzenesulphonyl chloride (2.21 g). Yield 3.2 g.

Workup

  1. customProcedure as for Example 1 (reaction performed at room temperature)

Sources & evidence

ORD record
ord-7302610fa58044c9ab85af1f98470193
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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