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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444050Generated: October 31, 2026

2-Mercaptoacetamide → HCID 59168102, compound

https://huagongshe.com/reaction/1444050

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MercaptoacetamideHCID 12961—
ReactantN-(5-Bromo-3-methoxy-2-pyrazinyl)-2,3-dichloro-N-[{2-(trimethylsilanyl)ethoxy}methyl]benzenesulphonamideHCID 59168156—
ProductHCID 59168102HCID 59168102—

Reaction Steps

Prepared as for Example 101b using N-(5-bromo-3-methoxy-2-pyrazinyl)-2,3-dichloro-N-[{2-(trimethylsilanyl)ethoxy}methyl]benzenesulphonamide (Example 55a) (0.2 g) and 2-mercaptoacetamide (0.05 g). The intermediate product containing the SEM group was purified by silica gel chromatography eluting with ethyl acetate/iso-hexane mixtures. Deprotection as for Example 101b gave the title compound. Yield 0.03 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662825B2
Source datasetuspto-grants-2010_02
ORD IDord-b9bf41097ea54add9cb8dbcc13cc9820
Source noteuspto-grants-2010_02