5-((Dimethylamino)methyl)-2-furanmethanol → HCID 59168107, compound

HRID 1444057Notes

Reaction equation

HRID 1444057 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][OH:11])=[CH:7][CH:6]=1)[CH3:3].Br[C:13]1[N:14]=[CH:15][C:16]([NH:20][S:21]([C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([Cl:30])[C:25]=2[Cl:31])(=[O:23])=[O:22])=[N:17][C:18]=1[Cl:19]>>[Cl:31][C:25]1[C:26]([Cl:30])=[CH:27][CH:28]=[CH:29][C:24]=1[S:21]([NH:20][C:16]1[C:15]([O:11][CH2:10][C:8]2[O:9][C:5]([CH2:4][N:2]([CH3:1])[CH3:3])=[CH:6][CH:7]=2)=[N:14][CH:13]=[C:18]([Cl:19])[N:17]=1)(=[O:23])=[O:22]

Participants

3

Reactant 2

HCID 849065-((Dimethylamino)methyl)-2-furanmethanolHCID 10126995HCID 10126995, compound

Product 1

HCID 59168107HCID 59168107, compound

Procedure

Prepared by the method of Example 31 using (5-dimethylaminomethyl-2-furanyl)methanol (0.2 g) and N-(3-bromo-6-chloro-2-pyrazinyl)-2,3-dichlorobenzenesulphonamide (Example 98) (0.3 g). Purified by silica gel chromatography eluting with methanol/dichloromethane mixtures. Yield 0.11 g.

Workup

  1. customPurified by silica gel chromatography
  2. washeluting with methanol/dichloromethane mixtures

Sources & evidence

ORD record
ord-c5a23d9606ec4646aa32a27ac9d269eb
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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