2-Cyanobenzenesulfonyl Chloride → HCID 59168153, compound

HRID 1444060Notes

Reaction equation

HRID 1444060 reaction equation
[Br:1][C:2]1[N:3]=[C:4]([O:9][CH3:10])[C:5]([NH2:8])=[N:6][CH:7]=1.[C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[S:19](Cl)(=[O:21])=[O:20])#[N:12]>>[Br:1][C:2]1[N:3]=[C:4]([O:9][CH3:10])[C:5]([NH:8][S:19]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[C:11]#[N:12])(=[O:21])=[O:20])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 5223472-Cyanobenzenesulfonyl ChlorideHCID 113447242-Amino-5-bromo-3-methoxypyrazine

Product 1

HCID 59168153HCID 59168153, compound

Procedure

Prepared by the method of Example 1 (reaction performed at room temperature) using 5-bromo-3-methoxy-2-pyrazinamine (0.2 g) and 2-cyanobenzenesulphonyl chloride (0.24 g).

Workup

  1. customPrepared by the method of Example 1 (reaction performed at room temperature)

Sources & evidence

ORD record
ord-fa3af27e77804d93aba2d0fdc0c97bfb
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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