Morpholine → HCID 10238198, compound

HRID 1444063Notes

Reaction equation

HRID 1444063 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([NH:12][C:13]1[C:18]([O:19][CH3:20])=[N:17][C:16]([CH:21]=O)=[CH:15][N:14]=1)(=[O:11])=[O:10].[NH:23]1[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([NH:12][C:13]1[C:18]([O:19][CH3:20])=[N:17][C:16]([CH2:21][N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[CH:15][N:14]=1)(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 59168180HCID 59168180, compound

Product 1

HCID 10238198HCID 10238198, compound

Procedure

Prepared as for Example 107b using 2,3-dichloro-N-(5-formyl-3-methoxy-2-pyrazinyl)benzenesulphonamide (Example 186a) (0.26 g) and morpholine (3.7 mL). Yield 0.057 g.

Workup

  1. customPrepared as for Example 107b

Sources & evidence

ORD record
ord-fec54c30910a4e73bbe4d811537685ef
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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