5-Amino-6-chloro-2,3-dicyanopyrazine → HCID 59168185, compound

HRID 1444084Notes

Reaction equation

HRID 1444084 reaction equation
[NH2:1][C:2]1[N:3]=[C:4]([C:11]#[N:12])[C:5]([C:9]#[N:10])=[N:6][C:7]=1Cl.[Cl:13][C:14]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][C:15]=1[S:21](Cl)(=[O:23])=[O:22].[CH3:25][O-:26].[Na+]>>[Cl:13][C:14]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][C:15]=1[S:21]([NH:1][C:2]1[C:7]([O:26][CH3:25])=[N:6][C:5]([C:9]#[N:10])=[C:4]([C:11]#[N:12])[N:3]=1)(=[O:23])=[O:22]

Participants

4

Reactant 3

HCID 6016455-Amino-6-chloro-2,3-dicyanopyrazineHCID 27342222,3-Dichlorobenzene-1-sulfonyl chlorideHCID 10942334Sodium Methoxide

Product 1

HCID 59168185HCID 59168185, compound

Procedure

Prepared by the method outlined in Example 1 using 5-amino-6-chloro-2,3-dicyanopyrazine (1.8 g) and 2,3-dichlorobenzenesulfonyl chloride (2.7 g). The adduct was reacted by the method outlined in example 31b using sodium methoxide to afford the sub-titled compound that was used directly.

Workup

  1. customPrepared by the method
  2. customThe adduct was reacted by the method

Sources & evidence

ORD record
ord-cf476336e499482bafec00b806944322
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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