HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium triethylboranuide → tert-Butyl (4-(hydroxymethyl)oxazol-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium triethylboranuide | HCID 5129078 | — |
| Reactant | Ethyl 2-[bis[(1,1-dimethylethoxy)carbonyl]amino]-4-oxazolecarboxylate | HCID 53419431 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | tert-Butyl (4-(hydroxymethyl)oxazol-2-yl)carbamate | HCID 45092179 | — |
Reaction Steps
Prepared by the method of Example 120 using 2-{bis[(1,1-dimethylethoxy)carbonyl]amino}-4-oxazolcarboxylic acid, ethyl ester (0.65 g) and sodium triethylborohydride (5.5 mL of a 1M solution in tetrahydrofuran). Yield 0.24 g. Used directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662825B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-21b68afb026240f7b1f6baadea62fb25 |
| Source note | uspto-grants-2010_02 |