HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-D-Tyr(Me)-L-Ile-D-Pro-OBzl → Boc-D-Tyr(Me)-L-Ile-D-Pro-OH
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-D-Tyr(Me)-L-Ile-D-Pro-OBzl | HCID 58726683 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Boc-D-Tyr(Me)-L-Ile-D-Pro-OH | HCID 131723245 | — |
Reaction Steps
Boc-D-Tyr(Me)-L-Ile-D-Pro-OBzl (1.44 g, 2.42 mmol) was dissolved in methanol (12 mL), and Pd—C (150 mg) was added. The mixture was stirred under hydrogen atmosphere at room temperature for 5 hours. Pd—C was filtered off, methanol was removed by evaporation, and the desired product was obtained as a foam. Yield: 1.21 g (2.4 mmol, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662778B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-a4cb3d7d1bbc4fab80a14583d4bcc4fc |
| Source note | uspto-grants-2010_02 |