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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444225Generated: November 1, 2026

4-(Trifluoromethoxy)phenylboronic acid → HCID 59654834, compound

https://huagongshe.com/reaction/1444225

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylboronic acidHCID 2734386—
Reactant(3-[(5-Bromo-furan-2-carbonyl)-amino]-phenyl)-acetic Acid Methyl EsterHCID 59654700—
ProductHCID 59654834HCID 59654834—

Reaction Steps

The methyl ester (16) (100 mg, 0.30 mmol) was coupled to 4-(trifluoromethoxy)-phenylboronic acid (67 mg, 0.33 mmol) using Method E. The crude compound was purified by column chromatography, eluting in 17% EtOAc in heptane to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662839B2
Source datasetuspto-grants-2010_02
ORD IDord-9bafe4f190964a90b385ec5ab9b24fbb
Source noteuspto-grants-2010_02