HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furan-2-boronic acid → {3-[([2,2']Bifuranyl-5-carbonyl)-amino]-phenyl}-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furan-2-boronic acid | HCID 2734357 | — |
| Reactant | (3-[(5-Bromo-furan-2-carbonyl)-amino]-phenyl)-acetic Acid Methyl Ester | HCID 59654700 | — |
| Product | {3-[([2,2']Bifuranyl-5-carbonyl)-amino]-phenyl}-acetic acid methyl ester | HCID 59654701 | — |
Reaction Steps
Methyl ester (16) (100 mg, 0.30 mmol) was coupled to furan-2-boronic acid (37 mg, 0.33 mmol) using Method E. The crude compound was purified by column chromatography, eluting in 17% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-463b8eb1ae704962b1c613c3df0dfb3f |
| Source note | uspto-grants-2010_02 |