Phenylboronic Acid → (3-[(4-Chloro-biphenyl-3-carbonyl)-amino]-phenyl)-acetic acid ethyl ester

関与物質

反応条件

反応手順

[3-(5-Bromo-2-chloro-benzoylamino)-phenyl]-acetic acid ethyl ester (198 mg, 0.50 mmol) was coupled to phenylboronic acid using Method E, except that the reaction mixture was heated at 80° C. for 25 min. The crude product was purified by column chromatography using 20% EtOAc in heptane to give the title compound.

情報源と証拠