6-Bromopyridine-2-carboxylic acid → HCID 59654644, compound

HRID 1444240Notes

Reaction equation

HRID 1444240 reaction equation
[Br:1][C:2]1[N:7]=[C:6]([C:8]([OH:10])=O)[CH:5]=[CH:4][CH:3]=1.[CH2:11]([O:13][C:14](=[O:23])[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH2:22])[CH:17]=1)[CH3:12]>>[CH2:11]([O:13][C:14](=[O:23])[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH:22][C:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([Br:1])[N:7]=2)=[O:10])[CH:17]=1)[CH3:12]

Participants

3

Reactant 2

HCID 5939196-Bromopyridine-2-carboxylic acidHCID 13042040Ethyl 2-(3-aminophenyl)acetate

Product 1

HCID 59654644HCID 59654644, compound

Procedure

6-Bromo-2-pyridinecarboxylic acid (113 mg, 0.56 mmol) was coupled with ethyl ester (6) (100 mg, 0.56 mmol) following Method C to give the title compound.

Sources & evidence

ORD record
ord-e467d8228fd5436b8263e74896f8fa0e
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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