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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444252Generated: November 1, 2026

3-Bromo-5-fluorobenzoic acid → [3-(3-Bromo-5-fluoro-benzoylamino)-phenyl]-acetic acid ethyl ester

https://huagongshe.com/reaction/1444252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-fluorobenzoic acidHCID 2773339—
ReactantEthyl 2-(3-aminophenyl)acetateHCID 13042040—
Product[3-(3-Bromo-5-fluoro-benzoylamino)-phenyl]-acetic acid ethyl esterHCID 59654737—

Reaction Steps

3-Fluoro-5-bromobenzoic acid (123 mg, 0.56 mmol) was coupled with ethyl ester (6) (100 mg, 0.56 mmol) following Method C to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662839B2
Source datasetuspto-grants-2010_02
ORD IDord-ecb55fbe715f4d6cacd8b12cee4adc15
Source noteuspto-grants-2010_02