Ethyl 2-(3-aminophenyl)acetate → HCID 59654790, compound

HRID 1444257Notes

Reaction equation

HRID 1444257 reaction equation
[Cl:1][C:2]1[S:3][CH:4]=[C:5]([C:7]([OH:9])=O)[N:6]=1.[CH2:10]([O:12][C:13](=[O:22])[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([NH2:21])[CH:16]=1)[CH3:11]>>[CH2:10]([O:12][C:13](=[O:22])[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([NH:21][C:7]([C:5]2[N:6]=[C:2]([Cl:1])[S:3][CH:4]=2)=[O:9])[CH:16]=1)[CH3:11]

Participants

3

Reactant 2

HCID 13042040Ethyl 2-(3-aminophenyl)acetateHCID 218030262-Chloro-1,3-thiazole-4-carboxylic acid

Product 1

HCID 59654790HCID 59654790, compound

Procedure

2-Chloro-thiazole-4-carboxylic acid (79) (70 mg, 0.43 mmol) was coupled with ethyl ester (6) (77 mg, 0.43 mmol) following Method C to give the title compound.

Sources & evidence

ORD record
ord-5057217db3c34fdd8ecd966b80861c93
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

Loading…