5-Phenylfuran-2-carboxylic acid → HCID 59654689, compound

HRID 1444264Notes

Reaction equation

HRID 1444264 reaction equation
[C:1]1([C:7]2[O:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:15]([O:17][C:18]([C:20]1[NH:21][C:22]2[C:27]([CH:28]=1)=[CH:26][C:25]([NH2:29])=[CH:24][CH:23]=2)=[O:19])[CH3:16]>>[CH2:15]([O:17][C:18]([C:20]1[NH:21][C:22]2[C:27]([CH:28]=1)=[CH:26][C:25]([NH:29][C:12]([C:10]1[O:11][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:8][CH:9]=1)=[O:14])=[CH:24][CH:23]=2)=[O:19])[CH3:16]

Participants

3

Reactant 2

HCID 7362555-Phenylfuran-2-carboxylic acidHCID 10726872Ethyl 5-amino-1H-indole-2-carboxylate

Product 1

HCID 59654689HCID 59654689, compound

Procedure

5-Phenyl-furan-2-carboxylic acid (56) (35 mg, 0.19 mmol) was coupled to 5-amino-1H-indole-2-carboxylic acid ethyl ester (42 mg, 0.20 mmol) using Method D to give the title compound.

Sources & evidence

ORD record
ord-f06c2ea04e7747bc88acd6879110f834
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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