HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(3-Chlorophenyl)furan-2-carboxylic acid → (3-[5-(3-Chloro-phenyl)-furan-2-carbonyl]-phenyl)-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| Reactant | (3-Amino-phenyl)-acetonitrile | HCID 4847850 | — |
| Product | (3-[5-(3-Chloro-phenyl)-furan-2-carbonyl]-phenyl)-acetonitrile | HCID 68490730 | — |
Reaction Steps
Carboxylic acid (65) (127 mg, 0.57 mmol) was coupled to aniline (80) (75 mg, 0.57 mmol) using Method C. The crude residue was purified by column chromatography eluting with 17% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-1addce32e6a44e679359a81a9ffe5717 |
| Source note | uspto-grants-2010_02 |