HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-furanecarboxylic acid → 5-Bromo-furan-2-carboxylic acid (3-cyanomethyl-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-furanecarboxylic acid | HCID 68511 | — |
| Reactant | (3-Amino-phenyl)-acetonitrile | HCID 4847850 | — |
| Product | 5-Bromo-furan-2-carboxylic acid (3-cyanomethyl-phenyl)-amide | HCID 59654859 | — |
Reaction Steps
5-Bromo-furan-2-carboxylic acid (1.68 g, 8.80 mmol) was coupled to aniline (80) (1.16 g, 8.80 mmol), using Method C. The residue was purified by column chromatography eluting with 20% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-f36610d7eb9642bc9d2b2c6cd3d3011b |
| Source note | uspto-grants-2010_02 |