HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-furanecarboxylic acid → 5-Bromo-furan-2-carboxylic acid [3-(2-cyano-vinyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-furanecarboxylic acid | HCID 68511 | — |
| Reactant | 3-(3-Amino-phenyl)-acrylonitrile | HCID 53425496 | — |
| Product | 5-Bromo-furan-2-carboxylic acid [3-(2-cyano-vinyl)-phenyl]-amide | HCID 72348819 | — |
Reaction Steps
5-Bromo-furan-2-carboxylic acid (716 mg, 3.75 mmol) was coupled to aniline (88) (540 mg, 3.75 mmol) using Method C. The residue was purified by column chromatography eluting with 20% EtOAc in heptane, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-e96dbd0e62c04011ad42e64486f0dfd7 |
| Source note | uspto-grants-2010_02 |