5-Bromo-2-furanecarboxylic acid → HCID 68491109, compound

HRID 1444303Notes

Reaction equation

HRID 1444303 reaction equation
[Br:1][C:2]1[O:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.[CH2:10]([O:12][C:13](=[O:25])[C:14](=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([NH2:24])[CH:19]=1)[CH2:15][CH3:16])[CH3:11]>>[CH2:10]([O:12][C:13](=[O:25])[C:14](=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([NH:24][C:7]([C:5]2[O:6][C:2]([Br:1])=[CH:3][CH:4]=2)=[O:9])[CH:19]=1)[CH2:15][CH3:16])[CH3:11]

Participants

3

Reactant 2

HCID 685115-Bromo-2-furanecarboxylic acidHCID 68497426HCID 68497426, compound

Product 1

HCID 68491109HCID 68491109, compound

Procedure

5-Bromo-furan-2-carboxylic acid (88 mg, 0.46 mmol) was coupled to 2-(3-amino-benzylidene)-butyric acid ethyl ester (100 mg, 0.46 mmol) using Method C to give the title compound.

Sources & evidence

ORD record
ord-5d5788f3b6b34452ac11021dbbf7a0b8
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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