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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444307Generated: October 31, 2026

(3-Phenylphenyl)boronic acid → HCID 68496617, compound

https://huagongshe.com/reaction/1444307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Phenylphenyl)boronic acidHCID 2734315—
Reactant3-{3-[(5-Bromo-furan-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl esterHCID 68494560—
ProductHCID 68496617HCID 68496617—

Reaction Conditions

Temperature100 °C

Reaction Steps

Bromo-derivative (99) (70 mg, 0.19 mmol) was coupled to biphenyl-3-boronic acid (42 mg, 0.21 mmol) acid using Method E, except that the reaction was heated at 100° C. The crude product was purified by column chromatography eluting with a stepped gradient of 0-10% EtOAc in heptane to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662839B2
Source datasetuspto-grants-2010_02
ORD IDord-21cfb138345340deb919d80d7a04d178
Source noteuspto-grants-2010_02