HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-fluorobenzoic acid → 3-[3-(5-Bromo-2-fluoro-benzoylamino)-phenyl]-acrylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-fluorobenzoic acid | HCID 2736315 | — |
| Reactant | 3-{3-[(5-Bromo-furan-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester | HCID 68494560 | — |
| Product | 3-[3-(5-Bromo-2-fluoro-benzoylamino)-phenyl]-acrylic acid ethyl ester | HCID 68497072 | — |
Reaction Steps
5-Bromo-2-fluorobenzoic acid (330 mg, 1.5 mmol) was coupled to aniline (99) (290 mg, 1.5 mmol) using Method C to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-490b3f7f40f144af84f7cb639b103c8e |
| Source note | uspto-grants-2010_02 |