Methanol → 1-Methyl-5-nitro-1H-indole-2-carboxylic acid methyl ester

HRID 1444326Notes

Reaction equation

HRID 1444326 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([N+:11]([O-:13])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[C:3]1[C:14]([OH:16])=[O:15].[CH3:17]O>>[CH3:17][O:15][C:14]([C:3]1[N:2]([CH3:1])[C:10]2[C:5]([CH:4]=1)=[CH:6][C:7]([N+:11]([O-:13])=[O:12])=[CH:8][CH:9]=2)=[O:16]

Participants

3

Reactant 2

HCID 887MethanolHCID 124775361-methyl-5-nitro-1H-indole-2-carboxylic acid

Product 1

HCID 155502671-Methyl-5-nitro-1H-indole-2-carboxylic acid methyl ester

Procedure

1-Methyl-5-nitro-1H-indole-2-carboxylic acid (99 mg, 0.45 mmol) was esterified with MeOH using Method A to give the title compound.

Sources & evidence

ORD record
ord-2c51b35b78674ff99a2d2eccda553e07
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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