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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444328Generated: October 25, 2026

5-Phenylfuran-2-carboxylic acid → 1-Methyl-5-[(5-phenyl-furan-2-carbonyl)-amino]-1H-indole-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1444328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Phenylfuran-2-carboxylic acidHCID 736255—
ReactantMethyl 5-amino-1-methyl-1h-indole-2-carboxylateHCID 59654636—
Product1-Methyl-5-[(5-phenyl-furan-2-carbonyl)-amino]-1H-indole-2-carboxylic acid methyl esterHCID 59654754—

Reaction Steps

Carboxylic acid (56) (23 mg, 0.12 mmol) was coupled to 5-amino-1-methyl-1H-indole-2-carboxylic acid methyl ester (25 mg, 0.12 mmol) using Method D to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662839B2
Source datasetuspto-grants-2010_02
ORD IDord-a3e52e3090b84f458e4b1b200a7334e7
Source noteuspto-grants-2010_02