HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(3-Aminophenyl)propionate → 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(3-Aminophenyl)propionate | HCID 82314 | — |
| Reactant | 5-(3,5-Dichlorophenyl)furan-2-carboxylic acid | HCID 4066369 | — |
| Product | 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-propionic acid ethyl ester | HCID 59654779 | — |
Reaction Steps
Carboxylic acid (67) (58 mg, 0.26 mmol) was coupled to aniline (124) (50 mg, 0.26 mmol) using Method C. The residue was purified by column chromatography eluting with 10% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-55bc9c6472464cc38e6a09a0646cc7a0 |
| Source note | uspto-grants-2010_02 |