6-Bromopyridine-2-carboxylic acid → HCID 24730153, compound

HRID 1444343Notes

Reaction equation

HRID 1444343 reaction equation
Br[C:2]1[N:7]=[C:6]([C:8]([OH:10])=[O:9])[CH:5]=[CH:4][CH:3]=1.[Cl:11][C:12]1[CH:13]=[C:14](B(O)O)[CH:15]=[C:16]([Cl:18])[CH:17]=1>>[Cl:11][C:12]1[CH:13]=[C:14]([C:2]2[N:7]=[C:6]([C:8]([OH:10])=[O:9])[CH:5]=[CH:4][CH:3]=2)[CH:15]=[C:16]([Cl:18])[CH:17]=1

Participants

3

Reactant 2

HCID 5939196-Bromopyridine-2-carboxylic acidHCID 27343313,5-Dichlorophenylboronic acid

Product 1

HCID 24730153HCID 24730153, compound

Procedure

6-Bromo-pyridine-2-carboxylic acid (500 mg, 2.47 mmol) was coupled to 3,5-dichloro-phenylboronic acid (473 mg, 2.47 mmol) acid using Method F to give the title compound.

Sources & evidence

ORD record
ord-3daa53e85a5e4011b7e9046903de3b5c
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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