Ethyl 2-(3-aminophenoxy)acetate → HCID 59654591, compound

HRID 1444345Notes

Reaction equation

HRID 1444345 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:14]=[C:13]([C:15]([OH:17])=O)[CH:12]=[CH:11][CH:10]=2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH2:18]([O:20][C:21](=[O:31])[CH2:22][O:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([NH2:30])[CH:25]=1)[CH3:19]>>[CH2:18]([O:20][C:21](=[O:31])[CH2:22][O:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([NH:30][C:15]([C:13]2[CH:12]=[CH:11][CH:10]=[C:9]([C:4]3[CH:5]=[C:6]([Cl:8])[CH:7]=[C:2]([Cl:1])[CH:3]=3)[N:14]=2)=[O:17])[CH:25]=1)[CH3:19]

Participants

3

Reactant 2

HCID 412308Ethyl 2-(3-aminophenoxy)acetateHCID 24730153HCID 24730153, compound

Product 1

HCID 59654591HCID 59654591, compound

Procedure

Carboxylic acid (131) (50 mg, 0.19 mmol) was coupled to aniline (64) (40 mg, 0.21 mmol) using Method D. The residue was triturated with TBME (3 ml) to give the title compound.

Workup

  1. customThe residue was triturated with TBME (3 ml)

Sources & evidence

ORD record
ord-fd7bfced16e841189df0c9aa322bab49
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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