HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(3-aminophenoxy)acetate → (3-{[6-(3-Chloro-phenyl)-pyridine-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(3-aminophenoxy)acetate | HCID 412308 | — |
| Reactant | 6-(3-Chlorophenyl)picolinic acid | HCID 24730135 | — |
| Product | (3-{[6-(3-Chloro-phenyl)-pyridine-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester | HCID 59654828 | — |
Reaction Steps
Carboxylic acid (136) (44 mg, 0.19 mmol) was coupled with aniline (64) (40 mg, 0.2 mmol) using Method D. The residue was purified by column chromatography eluting with 10% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662839B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-5a72bd5be9514255b11d375a89de119a |
| Source note | uspto-grants-2010_02 |