反应详情

The phenyl bromide (139) (100 mg, 0.25 mmol) was coupled to 3-fluoro-phenylboronic acid (34 mg, 0.24 mmol) using Method E. During this reaction, partial hydrolysis occurred. The residue was extracted using Work-up E1 to give a mixture of acid and ester, which was used without further purification.

1. customDuring this reaction, partial hydrolysis
2. extractionThe residue was extracted
3. customto give
4. customwas used without further purification