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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445038Generated: October 26, 2026

4-Fluoro-N-methylaniline → (4-Fluorophenyl)-methyl-(3-nitropyridin-2-ylmethyl)-amine

https://huagongshe.com/reaction/1445038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant2-(Bromomethyl)-3-nitropyridineHCID 21831178—
Product(4-Fluorophenyl)-methyl-(3-nitropyridin-2-ylmethyl)-amineHCID 6714195680%

Reaction Steps

In accordance with the same procedures as in Step 1 of Preparation 2, except for using 2-bromomethyl-3-nitropyridine prepared in Step 2 of Preparation 1 and (4-fluorophenyl)-methylamine, the titled compound was obtained as yellow solid. (Yield: 80%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662832B2
Source datasetuspto-grants-2010_02
ORD IDord-19575595350b4c72841d3097d79bb9d2
Source noteuspto-grants-2010_02