4-Methylbenzyl chloride → HCID 11666366, compound

HRID 1445051Notes

Reaction equation

HRID 1445051 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[NH:8][C:7]=12.[CH3:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18]Cl)=[CH:16][CH:15]=1>>[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][C:14]3[CH:21]=[CH:20][C:17]([CH3:18])=[CH:16][CH:15]=3)[C:7]=12

Participants

3

Reactant 2

HCID 77224-Methylbenzyl chlorideHCID 116369277-Chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 11666366HCID 11666366, compoundYield 75%

Procedure

In accordance with the same procedures as in Step 2 of Example 198, except for using 7-chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine prepared in Step 1 of Example 198 and 4-methylbenzyl chloride, the titled compound was obtained as a white solid. (Yield: 75%)

Sources & evidence

ORD record
ord-3fb9194a066643eebe5211b83afb803f
Source dataset
uspto-grants-2010_02
Patent number
US07662832B2

Reaction notes

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