Bicarbonate Ion → rac-(2'S,3'S,4'S)-6-chloro-2'-(3-chloro-2-fluoro-phenyl)-4'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-1'-carbonyl chloride
Reaction equation
[CH3:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:21]2[c:22]([F:28])[c:23]([Cl:27])[cH:24][cH:25][cH:26]2)[NH:13][CH2:14][CH:15]1[CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20].[Cl:41][C:42]([Cl:43])=[O:44].[Cl:45][CH2:46][Cl:47].[Na+:33].[O-:29][C:30]([OH:31])=[O:32]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:21]2[c:22]([F:28])[c:23]([Cl:27])[cH:24][cH:25][cH:26]2)[N:13]([C:42]([Cl:41])=[O:44])[CH2:14][CH:15]1[CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b58725fc64f04199a6a9129d612523f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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