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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445074Generated: November 2, 2026

1,2,3,4-Tetrahydroisoquinoline → HCID 67141191, compound

https://huagongshe.com/reaction/1445074

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-TetrahydroisoquinolineHCID 7046—
ReactantHCID 86615252HCID 86615252—
ProductHCID 67141191HCID 67141191—

Reaction Conditions

Temperature140 °C

Reaction Steps

1,2,3,4-Tetrahydroisoquinoline (1 ml) was added to 7-chloro-2-ethyl-3-methyl-1H-pyrrolo[2,3-c]pyridine (850 mg, 4.37 mmol) prepared in Preparation 28. The reaction mixture was stirred overnight at 140° C., cooled to room temperature, and then purified with silica gel column chromatography to give 660 mg of the titled compound as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662832B2
Source datasetuspto-grants-2010_02
ORD IDord-e3bfeedc05494c52af442ce63ff851c7
Source noteuspto-grants-2010_02