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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445405Generated: November 1, 2026

HCID 59644045, compound → HCID 24888490, compound

https://huagongshe.com/reaction/1445405

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59644045HCID 59644045—
Reactant(R)-4-((1R,4Z,8Z,13R,15R)-15-methoxy-5-methyl-3-oxo-2,14-dioxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-yl)-3-(4-methoxybenzyl)thiazolidin-2-oneHCID 59644077—
ProductHCID 24888490HCID 24888490—

Reaction Steps

Application of the method shown in Example 46, with the modification that (1R,4Z,8Z,13R,15R)-15-methoxy-15-((R)-3-(4-methoxybenzyl)-2-oxothiazolidin-4-yl)-5-methyl-14-oxa-2-aza-bicyclo[11.3.1]heptadeca-4,8-dien-3-one was substituted for (R)-4-((1R,4Z,8Z,13R,15R)-15-methoxy-5-methyl-3-oxo-2,14-dioxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-yl)-3-(4-methoxybenzyl)thiazolidin-2-one, afforded the title compound, together with the 8E-isomer.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666861B2
Source datasetuspto-grants-2010_02
ORD IDord-4d42b7c1590841a085c10372ffb73455
Source noteuspto-grants-2010_02