HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-methylaniline → 4-Methyl-2-thiazol-2-yl-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-methylaniline | HCID 11422 | — |
| Reactant | 2-(Tributylstannyl)-1,3-thiazole | HCID 2763259 | — |
| Product | 4-Methyl-2-thiazol-2-yl-phenylamine | HCID 13718383 | 8% |
Reaction Steps
2-Tributylstannanyl-thiazole (600 mg, 1.6 mmol) was reacted with 2-bromo-4-methylaniline (220 mg, 1.2 mmol) according to general procedure [B] for the preparation of substituted anilines described above, which gave the title compound (17 mg, 8%). [M+1] 191.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666834B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-14897ca97dd448559d8ec2f143349f47 |
| Source note | uspto-grants-2010_02 |