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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445640Generated: October 27, 2026

4-Fluoro-3-methoxybenzenesulfonyl chloride → 4-Cyano-3-ethoxybenzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1445640

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Reactant4-Amino-2-ethoxybenzonitrileHCID 23068073—
Product4-Cyano-3-ethoxybenzene-1-sulfonyl chlorideHCID 55280879—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 4-amino-2-ethoxy-benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666878B2
Source datasetuspto-grants-2010_02
ORD IDord-c1a2f2897de144c6b850c9a4fe1c4ad9
Source noteuspto-grants-2010_02