2-Methoxy-4-nitrobenzonitrile → 4-Cyano-3-methoxybenzenesulfonyl chloride

HRID 1445642Notes

Reaction equation

HRID 1445642 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[O:13][CH2:14]C)#[N:2].COC1C=C([N+]([O-])=O)C=CC=1C#N>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[O:13][CH3:14])#[N:2]

Participants

3

Reactant 2

HCID 2918672-Methoxy-4-nitrobenzonitrileHCID 552808794-Cyano-3-ethoxybenzene-1-sulfonyl chloride2×

Product 1

HCID 552792354-Cyano-3-methoxybenzenesulfonyl chloride

Procedure

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 2-methoxy-4-nitro-benzonitrile.

Sources & evidence

ORD record
ord-dbf6cd0bee474034a1b4bf213d42373c
Source dataset
uspto-grants-2010_02
Patent number
US07666878B2

Reaction notes

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