1-Bromopropane → 4-Cyano-3-propoxybenzenesulfonyl chloride

HRID 1445643Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[O:13][CH2:14][CH3:15])#[N:2].Br[CH2:17]CC>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[O:13][CH2:14][CH2:15][CH3:17])#[N:2]

Participants

Reactant 2

HCID 78401-Bromopropane

HCID 552808794-Cyano-3-ethoxybenzene-1-sulfonyl chloride2×

Product 1

HCID 866201504-Cyano-3-propoxybenzenesulfonyl chloride

Procedure

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing bromoethane with 1-bromopropane.

Sources & evidence

ORD record: ord-050ea674e32844198b28eba69d99f79a
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07666878B2

Reaction notes

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