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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445648Generated: October 26, 2026

2-Methyl-4-nitrobenzonitrile → 4-Cyano-3-methylbenzenesulfonyl chloride

https://huagongshe.com/reaction/1445648

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-4-nitrobenzonitrileHCID 4346367—
Reactant4-Cyano-3-ethoxybenzene-1-sulfonyl chlorideHCID 55280879—
Product4-Cyano-3-methylbenzenesulfonyl chlorideHCID 55280150—

Reaction Steps

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 2-methyl-4-nitro-benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666878B2
Source datasetuspto-grants-2010_02
ORD IDord-28cf79bc53114fe5b25453b48ef0d266
Source noteuspto-grants-2010_02