Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445657Generated: October 27, 2026

4-Amino-2-fluorobenzotrifluoride → 3-Fluoro-4-(trifluoromethyl)benzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1445657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-fluorobenzotrifluorideHCID 2735914—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product3-Fluoro-4-(trifluoromethyl)benzene-1-sulfonyl chlorideHCID 86620153—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 3-fluoro-4-trifluoromethyl-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666878B2
Source datasetuspto-grants-2010_02
ORD IDord-5d9f1a814ebf49399d59cf1e1d5d9166
Source noteuspto-grants-2010_02