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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445659Generated: November 1, 2026

4-Chloro-3-(trifluoromethyl)aniline → 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride

https://huagongshe.com/reaction/1445659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-(trifluoromethyl)anilineHCID 67574—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product4-Chloro-3-(trifluoromethyl)benzenesulfonyl ChlorideHCID 2780719—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 4-chloro-3-trifluoromethyl-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666878B2
Source datasetuspto-grants-2010_02
ORD IDord-7cb39ee19fc44fd7ac5783de102fc4f0
Source noteuspto-grants-2010_02