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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445679Generated: October 25, 2026

Hydrochloric Acid → Ethyl 2-(2-methyl-3,5-dioxo-1,2,4-thiadiazolidin-4-yl)acetate

https://huagongshe.com/reaction/1445679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethyl IsocyanateHCID 12228—
ReactantAcetic acid, 2-isothiocyanato-, ethyl esterHCID 32202—
ReactantPotassium PermanganateHCID 516875—
ProductEthyl 2-(2-methyl-3,5-dioxo-1,2,4-thiadiazolidin-4-yl)acetateHCID 6539175—

Reaction Steps

Reagents: Ethyl isothiocyanatoacetate (0.8 ml, 6.5 mmol), 35% HCl (3.1 ml), KMnO4 (0.5 g), methyl isocyanate (0.38 ml, 6.5 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666885B2
Source datasetuspto-grants-2010_02
ORD IDord-d355457539e9403bb7f98950292df02b
Source noteuspto-grants-2010_02