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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445682Generated: October 25, 2026

Hydrochloric Acid → 2-Ethyl-4-(4-nitrophenyl)-1,2,4-thiadiazolidine-3,5-dione

https://huagongshe.com/reaction/1445682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl isocyanateHCID 8022—
ReactantBenzene, 1-isothiocyanato-4-nitro-HCID 75044—
ReactantPotassium PermanganateHCID 516875—
SolventTetrahydrofuranHCID 8028—
Product2-Ethyl-4-(4-nitrophenyl)-1,2,4-thiadiazolidine-3,5-dioneHCID 6539173—

Reaction Steps

Reagents: 4-nitrophenyl isothiocyanate (1.17 g, 6.5 mmol), 35% HCl (3.1 ml), KMnO4 (0.5 g), ethyl isocyanate (0.51 ml, 6.5 mmol) in THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666885B2
Source datasetuspto-grants-2010_02
ORD IDord-1160c128ee8e45b9a2aa41d837345855
Source noteuspto-grants-2010_02