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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445691Generated: October 26, 2026

Maleimide → 1-(2-(4-methoxyphenyl)ethyl)-2,5-dihydro-1H-pyrrole-2,5-dione

https://huagongshe.com/reaction/1445691

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMaleimideHCID 10935—
ReactantTriphenylphosphineHCID 11776—
Reactant4-Methoxyphenethyl alcoholHCID 69705—
ReactantDiethyl azodicarboxylateHCID 5462977—
Product1-(2-(4-methoxyphenyl)ethyl)-2,5-dihydro-1H-pyrrole-2,5-dioneHCID 2392392—

Reaction Steps

Reagents: Ph3P (1.31 g, 5 mmol), DEAD (0.8 ml, 5 mmol), p-methoxyphenethyl alcohol (1.2 g, 7.5 mmol) and maleimide (0.48 g, 5 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666885B2
Source datasetuspto-grants-2010_02
ORD IDord-7666a4646ce243998d18a08dc80dca1b
Source noteuspto-grants-2010_02