Sodium methanethiolate → 2-Methanesulfonyl-5-iodo-pyridine

HRID 1445759Notes

Reaction equation

[CH2:1]([S:3]([C:6]1[CH:11]=[CH:10][C:9]([I:12])=[CH:8][N:7]=1)(=[O:5])=[O:4])C.C[S-].[Na+]>>[CH3:1][S:3]([C:6]1[CH:11]=[CH:10][C:9]([I:12])=[CH:8][N:7]=1)(=[O:4])=[O:5]

Participants

Reactant 2

HCID 4378561Sodium methanethiolate

HCID 589514652-Ethanesulfonyl-5-iodo-pyridine

Product 1

HCID 589514522-Methanesulfonyl-5-iodo-pyridine

Procedure

The titled compound is prepared substantially in accordance with the procedure of Intermediate 22 using sodium methanethiolate in place of sodium ethanethiolate.

Sources & evidence

ORD record: ord-b11f9272bbfc4a749c13a5a9a1272286
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07666871B2

Reaction notes

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