HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid monohydrate → HCID 131727894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | tert-Butyl (3R)-3-hydroxypyrrolidine-1-carboxylate | HCID 6544479 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 131727894 | HCID 131727894 | 98.2% |
Reaction Steps
Prepare using the method of Intermediate 49 with p-toluenesulfonic acid monohydrate (0.255 g, 1.34 mmol), N-Boc-(R)-(−)-3-pyrrolidinol (0.251 g, 1.34 mmol) and ethanol (5 mL) to give the title compound as a pale yellow oil (0.34 g): MS (m/e): 88 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666871B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-2a1ab66394c24e31b2ee0eec5cadc486 |
| Source note | uspto-grants-2010_02 |