HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid monohydrate → HCID 131727895, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | tert-Butyl (3S)-3-hydroxypyrrolidine-1-carboxylate | HCID 854055 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 131727895 | HCID 131727895 | 101.1% |
Reaction Steps
Prepare using the method of Intermediate 49 with p-toluenesulfonic acid monohydrate (0.254 g, 1.34 mmol), N-Boc-(S)-(+)-3-pyrrolidinol (0.250 g, 1.34 mmol) and ethanol (2 mL) to give the title compound as a white solid (0.35 g): MS (m/e): 88 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666871B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-20979d24ab5d41cab0467a9994114dda |
| Source note | uspto-grants-2010_02 |