2-(Bromomethyl)pyridine hydrobromide → HCID 58951436, compound

HRID 1445784Notes

Reaction equation

HRID 1445784 reaction equation
[CH2:1]([O:3][C:4](=[O:18])[CH2:5][C:6]1[N:7]=[C:8]([C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=2)[O:9][CH:10]=1)[CH3:2].Br.Br[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=1>>[CH2:1]([O:3][C:4](=[O:18])[CH2:5][C:6]1[N:7]=[C:8]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=3)=[CH:13][CH:12]=2)[O:9][CH:10]=1)[CH3:2]

Participants

3

Reactant 2

HCID 27347202-(Bromomethyl)pyridine hydrobromideHCID 136021432HCID 136021432, compound2×

Product 1

HCID 58951436HCID 58951436, compound

Procedure

The title compound is prepared in a manner substantially similar to Intermediate 16 from [2-(4-Hydroxy-phenyl)-oxazol-4-yl]-acetic acid ethyl ester (See Intermediate 64) and 2-(bromomethyl)pyridine hydrobromide. MS (m/e): 339.2 (M+1)

Sources & evidence

ORD record
ord-5348b0a91a504ebc8dede0d4832c00b4
Source dataset
uspto-grants-2010_02
Patent number
US07666871B2

Reaction notes

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