2-Methylpiperidine → HCID 11508283, compound
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][CH:10]=[C:11]([CH2:13]Cl)[N:12]=2)=[CH:4][CH:3]=1.[CH3:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][NH:17]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][CH:10]=[C:11]([CH2:13][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH:16]3[CH3:15])[N:12]=2)=[CH:4][CH:3]=1Participants
3
Procedure
The titled compound is prepared substantially in accordance with the procedure of Example 16 using 2-(4-Bromo-phenyl)-4-chloromethyl-oxazole (See Intermediate 1) and 2-methylpiperidine. MS (m/e): 336.2 (M+1)
Sources & evidence
- ORD record
- ord-04376a78c17546f3a5af5614c7d564a2
- Source dataset
- uspto-grants-2010_02
- Patent number
- US07666871B2
Reaction notes
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