(2H-1,3-benzodioxol-5-yl)boronic acid → HCID 11639427, compound

HRID 1445805Notes

Reaction equation

HRID 1445805 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][C:3]=2[O:2]1.Br[C:14]1[CH:19]=[CH:18][C:17]([C:20]2[O:21][C:22]([CH3:32])=[C:23]([CH2:25][CH2:26][N:27]3[CH2:31][CH2:30][CH2:29][CH2:28]3)[N:24]=2)=[CH:16][CH:15]=1>>[O:9]1[C:8]2[CH:7]=[CH:6][C:5]([C:14]3[CH:19]=[CH:18][C:17]([C:20]4[O:21][C:22]([CH3:32])=[C:23]([CH2:25][CH2:26][N:27]5[CH2:28][CH2:29][CH2:30][CH2:31]5)[N:24]=4)=[CH:16][CH:15]=3)=[CH:4][C:3]=2[O:2][CH2:1]1

Participants

3

Reactant 2

HCID 2734371(2H-1,3-benzodioxol-5-yl)boronic acidHCID 116815462-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Product 1

HCID 11639427HCID 11639427, compound

Procedure

The title compound is prepared in a manner substantially analogous to Example 35 starting from 3,4-Methylenedioxybenzene boronic acid and 2-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole. MS (m/e): 377.1 (M+1)

Sources & evidence

ORD record
ord-c75f257a2e8e4fc2b3112674a7527a7e
Source dataset
uspto-grants-2010_02
Patent number
US07666871B2

Reaction notes

Loading…