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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1445806Generated: November 3, 2026

2,4-Dimethoxybenzeneboronic acid → 2-(2',4'-Dimethoxy-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

https://huagongshe.com/reaction/1445806

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dimethoxybenzeneboronic acidHCID 2734341—
Reactant2-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazoleHCID 11681546—
Product2-(2',4'-Dimethoxy-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazoleHCID 11545628—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Example 35 starting from 2,4-Dimethoxybenzene boronic acid and 2-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole. MS (m/e): 393.2 (M+1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666871B2
Source datasetuspto-grants-2010_02
ORD IDord-6b5d5fbbb7f7417cacf9593e2276c391
Source noteuspto-grants-2010_02